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June 2017

THINGS YOU SHOULD KNOW ABOUT SICKLE CELL ANEMIA

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Sickle cell anemia is an inherited form of blood disorder — a condition in which there aren’t enough healthy red blood cells to carry adequate oxygen throughout your body.

Usually, the red blood cells are flexible and round (doughnut shape), moving easily via the blood vessels. In the case of sickle cell, the red blood cells are sickle in shape, they are not flexible rather are sticky and rigid. These c- shaped cells can get stuck in small blood vessels, which can reduce or block blood flow and oxygen to parts of the body.

SIGNS & SYMPTOMS

The symptoms and signs of sickle cell anemia vary from person to person over time.

It is very easy for the sickle cells to die, leaving no red blood cells. Usually red blood cells live for 120days before replacement, but sickle cell dies in 10-20days, leaving shortage of oxygen and red blood cells causing anemia & fatigue.

Episodes of pain called crises are a major symptom of sickle cell anemia. The pain develops when the sickle red blood cells flow through tiny blood vessels to their chest, abdomen and joins. Pain can also occur in their bones.

If crisis is severe, patients need to be hospitalized. Some adults and adolescents with sickle cell anemia also have chronic pain which can results to bone/joint damage, ulcer, stroke etc.

Painful swelling of hands and feet: The swelling is caused by sickle-shaped red blood cells blocking blood flow to the hands and feet.

Frequent infections: Sickle cells can damage an organ that fights infection (spleen), leaving you more vulnerable to infections. Doctors commonly give infants and children with sickle cell anemia vaccinations and antibiotics to prevent potentially life-threatening infections, such as pneumonia.

Delayed growth: Red blood cells provide your body with the oxygen and nutrients you need for growth. A shortage of healthy red blood cells can lead to stunted growth in infants and children and delay puberty in teenagers.

Vision problems: Tiny blood vessels that supply your eyes may become plugged with sickle cells.

A sickle cell patient should see a doctor immediately or seek emergency medical care when he/she has:

  • One-sided paralysis or weakness
  • Trouble walking or talking
  • Vision problem
  • Headache
  • Swelling of the hand or feet
  • Unexplained episodes of severe pain

MANAGEMENT OF SICKLE CELL

Sickle cell anemia is efficiently managed with Drepanostat (Hydroxymethylbenzoic acid).

This is a sickle cell management drug which comes in 10mg capsules. Drepanostat inhibits sickling of the red blood cells by enhancing its oxygen carrying capacity through increased production of Fetal Hemoglobin in the body. It is safe and well tolerated in infants and adults.

Drepanostat can be used during crisis and also as prophylaxis.

 

Where to buy?

Email: info@bolarpharm.com

Address: 5 Talabi Street, off Adeniyi Jones Avenue, Ikeja

Tel: +234 903 2600 077

Fax: ++234 708 7054 296

PERFECTIL® ORIGINAL. PIONEERING, ORIGINAL TRIPLE ACTIVE SUPPORT FOR SKIN, HAIR AND NAILS.

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Over 20 micronutrients including:-

  • Vitamins B2, B3 and biotin which contribute to the maintenance of normal skin.
  •  Vitamin C contributes to normal collagen formation for the normal function of skin.
  • Minerals selenium and zinc which contribute to the maintenance of normal hair and nails
  •  Also contains Grape Seed extract and Natural Mixed Carotenoids

Grape seed extract- contains antioxidants to help protect cells from free radical damage and promote a healthy circulation

Natural mixed carotenoids – act as antioxidants within the body, can help reduce sun damage and helps fight against ageing. Converts to vitamin A naturally in the body.

L-Cystine – an amino acid necessary for nail growth. Comprehensive formula, no need to take an additional multivitamin

Pack contains: 30 or 90 tablets. Take one per day.

Nutritional Information:

• No artificial colours

• No preservatives

• No salt, yeast or lactose

• Gluten free

• No gelatin

• Suitable for vegetarians

• Perfectil® is not tested on animals

One tablet per day, to replace all other multivitamins.

PERFECTIL® PLUS SKIN. EXPERT SUPPORT FOR SKIN, HAIR AND NAILS.

All the benefits of the original Perfectil® tablet plus a specialist Nutri-dermal TMcapsule to provide

additional nutrient levels.

Original Perfectil® tablet with over 20 micronutrients, including:-

  •  Vitamins B2, B3 and biotin which contribute to the maintenance of normal skin
  •  Vitamin C contributes to normal collagen formation for the normal function of skin
  • Minerals selenium and zinc which contribute to the maintenance of normal hair and nails
  • Also contains Grape Seed extract and Natural Mixed Carotenoids

Each Nutri-dermalTM capsule includes:

  •  Extra biotin††, which contributes to the maintenance of normal skin
  •  Essential Omega-3 fatty acids from fish oil and Omega-6 fatty acids from Starflower and Blackcurrant Seed Oil
  •  Also contains Lutein, Lycopene extract and Co-Q10

Omega-3 Fish Oil: Can help cells repair and prevent damage. May also help the body resist sunburn, and help reduce fine lines, wrinkles, and ease dry skin

Starflower Oil: is a rich source of Omega-6 fatty acids which are important to help prevent dry skin

Blackcurrant Seed Oil: Provides the plant world’s richest known natural source of Omega-3 and Omega-6. These important fatty acids may help to keep skin supple and toned.

Lutein: helps protect skin from free radical damage particularly that induced by UV radiation

Lycopene Extract: Can play a valuable role in protecting vulnerable skin from the sun’s UV radiation, which can contribute to premature skin damage.

Co-Q10: As well as being an antioxidant it has been shown to decrease the activity of certain enzymes that degrade collagen present in skin.

All in one convenient pack:

28 Perfectil® Original tablets. Take one per day.

28 Nutri-Dermal™ capsules. Take one per day.

Nutritional Information:

  • Gluten free
  • No artificial colours
  • No preservatives
  • No salt or yeast

Perfectil is not tested on animals. One tablet and one capsule per day, to replace all other multivitamins.

PERFECTIL® PLUS HAIR. EXPERT SUPPORT FOR SKIN, HAIR AND NAILS.

All the benefits of the original Perfectil® tablet formulated with extra support for hair. Over 25 micronutrients including:-

  •  Colourel® Blend with copper which contributes to normal hair pigmentation.
  • Biotin, selenium and zinc which contribute to the maintenance of normal hair.
  • Selenium which contributes to the maintenance of normal nails
  • Zinc and iodine which contribute to the maintenance of normal skin
  • Vitamin C which contributes to normal collagen formation
  • Also contains amino acids Marine Collagen, Horsetail Powder extract, Inositol, Grapeseed extract and Co-Q10.

Pack contains : 60 Perfectil ® Plus Hair tablets. Take two per day.

Nutritional Information

• No gelatin

• Gluten free

• No artificial colours

• No preservatives

• No salt, yeast or lactose

• Suitable for vegetarians

• Perfectil is not tested on animals

Two tablets per day, to replace all other multivitamins

PERFECTIL® PLUS NAILS. EXPERT SUPPORT FOR SKIN, HAIR AND NAILS.

All the benefits of the original Perfectil® tablet formulated with extra support for nails. Over 25 micronutrients including:-

  •  Extra selenium†† which contributes to the maintenance of normal nails
  • Vitamin C which contributes to normal collagen function
  • Copper which contributes to the maintenance of normal connective tissues
  • Also contains Horsetail Botanical, Grape Seed Extract, MSM, L-cystine and Co-enzyme Q10

Horsetail extract: a natural source of silica, to help keep your nails supple. Horsetail contains minerals that may help with weak and brittle fingernails and white spots in the nails helping to strengthen and repair.

Grape Seed Extract: contains antioxidants to help protect cells from free radical damage and promote a healthy circulation.

Methyl Sulphonyl Methane (MSM): Necessary for collagen synthesis in skin, hair and nails. MSM provides sulphur, which an important nutrient is required for the healthy growth of collagen and keratin which is found in the outer layer of the skin, hair and nails.

L-Cystine: amino acid necessary for nail growth.

Co-Q10: an antioxidant that has been shown to decrease the activity of certain enzymes that degrade collagen

Pack contains: 60 Perfectil ® Plus Nails tablets. Take two per day.

NUTRITIONAL INFORMATION

  • No gelatin
  • Gluten free
  • No artificial colours
  • No preservatives
  • No salt, yeast or lactose

Suitable for vegetarians

Perfectil is not tested on animals

Two tablets per day, to replace all other multivitamins.

PERFECTIL® PLUS PROTAN™. TRIPLE ACTIVE SUPPORT FOR SKIN, HAIR AND NAILS PLUS PROTAN™

Perfectil® PROTAN™ combines the original Perfectil® tablet formula with a copper-biotin nutrient blend to contribute to normal skin pigmentation and cell protection. Skin pigmentation (melanin) serves as a light filter for the protection of tissues against ultraviolet light

damage.

Appeals to women who are looking to support and retain a healthy looking suntan.

Perfectil® PROTAN™ has over 25 micronutrients including:-

  •  1000mcg of Copper which contributes to normal skin and hair pigmentation.
  • Biotin contributes to the maintenance of normal skin.
  • Also contains L-Tyrosine, Lycopene, C0-Q10, Grape Seed, Green Tea and Carrot extracts
  •  L-Tyrosine supports the production of the melanin pigment.
  • Lycopene can play a valuable role in protecting vulnerable skin from the sun’s UV radiation, which can contribute to premature skin damage.
  • Green Tea Extract helps to protect cells from oxidative damage
  • Carrot Extract provides high concentration of carotenoids reducing the damaging effects of free radicals.
  • Co-Q10, as well as being an antioxidant it has been shown to decrease the activity of certain enzymes that degrade collagen present in skin.

NUTRITIONAL INFORMATION

• Gluten free

• No gelatin

• No artificial colours

• No preservatives

• No salt, yeast or lactose

• Perfectil is not tested on animals

Two tablets per day, to replace all other multivitamins.

PERFECTIL® MAX. MAXIMUM TRIPLE ACTIVE SUPPORT FOR SKIN, HAIR AND NAILS.

Perfectil ® Max is designed for those who are seeking maximum nutritional care from Perfectil ®with the advanced Perfectil Plus† tablet PLUS a specialist Nutri-dermal™ capsule.

Perfectil ® Plus tablet with over 25 micronutrients including:-

  •  Extra selenium†† which contributes to the maintenance of normal nails
  • Vitamin C which contributes to normal collagen function
  • Copper which contributes to the maintenance of normal connective tissues
  • Also contains Grape Seed extract, Horsetail powder extract, MSM, Lutein Esters and Co-Q10

Each Nutri-dermalTM capsule includes:

  •  Extra biotin††, which contributes to the maintenance of normal skin
  • Essential Omega-3 fatty acids from fish oil and Omega-6 fatty acids from Starflower and Blackcurrant Seed Oil
  • Also contains Lutein and Lycopene extract
  • Horsetail extract: a natural source of silica, to help keep your nails supple. Horsetail contains minerals that may help with weak and brittle fingernails and white spots in the nails helping to strengthen and repair.
  • Grape Seed Extract: contains antioxidants to help protect cells from free radical damage and promote a healthy circulation.

Methyl Sulphonyl Methane (MSM): necessary for collagen synthesis in skin, hair and nails. MSM provides sulphur, which is an important nutrient required for the healthy growth of collagen and keratin which is found in the outer layer of the skin, hair and nails.

  •  L-Cystine: amino acid necessary for nail growth.
  • Co-Q10: an antioxidant that has been shown to decrease the activity of certain enzymes that degrade collagen
  • Omega-3 Fish Oil: Can help cells repair and prevent damage. May also help the body resist sunburn, and help reduce fine lines, wrinkles, and ease dry skin
  • Starflower Oil: is a rich source of Omega-6 fatty acids which are important to help prevent dry skin
  • Blackcurrant Seed Oil: Provides the plant world’s richest known natural source of Omega-3 and Omega-6. These important fatty acids may help to keep skin supple and toned.
  • Lutein: helps protect skin from free radical damage particularly that induced by UV radiation
  • Lycopene Extract: Can play a valuable role in protecting vulnerable skin from the sun’s UV radiation, which can contribute to premature skin damage.

PERFECTIL® MAX. MAXIMUM TRIPLE ACTIVE SUPPORT FOR SKIN, HAIR AND NAILS.

The most comprehensive formula in the range, all in one convenient pack. Perfectil Max is designed for those who are seeking maximum nutritional care from Perfectil with the advanced Perfectil Plus† tablet PLUS a specialist Nutri-dermal™ capsule.

Perfectil Plus tablet with over 28 micronutrients, including:

  •  Extra selenium†† which contributes to the maintenance of normal nails.
  •  Vitamin C which contributes to normal collagen function for the normal function of skin and blood vessels.
  • Copper which contributes to the maintenance of normal connective tissues.

Each Nutri-dermal™ capsule contains:

  •  Extra biotin†† which contributes to the maintenance of normal skin.
  • Essential Omega-3 fatty acids from fish oil and Omega-6
  • Fatty acids from Starflower and Blackcurrant Seed Oil.
  • Lutein, Co-enzyme Q10 and Lycopene .

Nutritional Information:

  • Gluten free
  • No artificial colours
  • No preservatives
  • No salt, yeast or lactose

Perfectil is not tested on animals

Two tablets and one capsule per day, to replace all other multivitamins.

Pack contains:

56 Perfectil® Plus tablets. Take two per day.

28 Nutri- Dermal™ capsules. Take one per day.

PERFECTIL ® PLATINUM. ULTIMATE TIMEDEFY TM FORMULA

A major advance in skin nutrition, specifically targeted towards maintaining a radiant skin complexion.

  •  Unique 30 ingredient ‘cell renewal’ formula with Marine Collagen and antioxidants.
  • Nutrients contribute to both cell protection and cell division.
  • Skin and collagen formation
  • Vitamin C contributes to normal collagen formation, the substance that helps to keep skin supple.
  • Vitamins B2, B3 and biotin contribute to the maintenance of normal skin.
  • Cell division and protection

The most significant cause of premature skin ageing is sunlight (UV radiation) as well as pollution, smoking and the high levels of damaging free radicals this generates.

  •  Antioxidant vitamins C, E and Riboflavin (B2) contribute to the protection of cells from oxidative damage.
  • Vitamins D and B12, folic acid, magnesium and zinc contribute to the maintenance of normal cell division.

Nail and hair support –

  • Selenium and zinc contribute to the maintenance of normal nail health.
  • Biotin contributes to normal hair health with copper which contributes to normal hair pigmentation.
  • Also includes Grape Seed, Pine Bark, Green Tea and Tomato extracts, Blackcurrant Seed Oil, Alpha Lipoic Acid and Co-Q10
  • Designed to be used in place of your usual multivitamin or Perfectil® supplement

Pack contains:30 or 60 Perfectil ® Platinum tablets. Take two per day.

Nutritional Information.

• No gelatin

• Gluten free

• No artificial colours

• No preservatives

• No salt or yeast

• Suitable for vegetarians

• Perfectil Platinum is not tested on animals

Two tablets per day, to replace all other multivitamins.